Glyxambi: Steer Clear Of This New Diabetes Drug

| April 14, 2015

Rubber-stamping risky new diabetes drugs at a record pace seems to be the latest mainstream trend. Recently, Trulicity, a once-a-week injection from Eli Lilly and Co, was fast-tracked onto both the American and European markets, despite serious concerns over its safety.

With diabetes rates skyrocketing and fierce competition among those in the drug industry, pharmaceutical companies are hatching plans to combine some of their most dangerous diabetes drugs… medications that have been linked to heart disease and even cancer… into new, dangerous formulations they hope will rake in billions.

It’s all about the money

Glyxambi (manufactured by Eli Lilly and Boehringer Ingelheim) has recently been approved by the American Food and Drug Administration (FDA) and the first thing you should know about this drug is that it is not the brand-spanking-new breakthrough drug it is made out to be. In fact, it’s a combination of two very risky diabetes drugs.

The first half of this horror was approved last summer under the brand name Jardiance — known as a SGLT2 inhibitor that forces your kidneys to excrete glucose in your urine.

While peeing your diabetes away may sound like a good idea, once you realise that Jardiance can trigger a deadly drop in blood pressure that can cause everything from dizziness to dangerous falls, you’ll want to steer clear of this drug at all costs.

SGLT2 inhibitors like Jardiance have also been linked to what experts call “a cascade of adverse events,” including urinary tract infections and serious kidney and heart problems.

And here’s the worst part — Jardiance is not the most dangerous drug in the Glyxambi-combination.

The second half of this two-drug cocktail is called Tradjenta, which mimics a natural hormone in your body called GLP-1 that controls blood sugar.

It also sends your risk of pancreatic and thyroid cancer through the roof.

The Institute for Safe Medicine Practices found that compared to older type 2 diabetes treatments, such as metformin, your risk of pancreatitis and pancreatic cancer is 25 times higher on these GLP-1 medications like Tradjenta.

But it’s not like the makers of Glyxambi are even trying to hide these hideous side effects, because the warning label on Glyxambi clearly says it increases your risk of “pancreatitis which may be severe and lead to death.” Pancreatitis, a severe swelling of your pancreas, is also a major risk factor for pancreatic cancer.

So if your doctor mentions some new way to treat your type 2 diabetes, remember, Glyxambi is a potentially deadly cocktail of two very dangerous diabetes drugs in one.

The only “new” thing about Glyxambi is its name. That, and the double dose of danger you get from it.

Wishing you the best of health,

Francois Lubbe
Editor
Real Diabetes Truth

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Reference

“US launch for BI/Lilly diabetes combo Glyxambi” Selina McKee, March 23, 2015, PharmaTimes, pharmatimes.com

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Category: Diabetes Drugs

Comments (11)

Testimonials are based on the personal experience of individuals. Results are not typical and the potential benefits of taking any drug or supplement may vary depending on your individual needs and health requirements. Please consult your GP before making any changes to your medical regimen.

  1. Jodie says:

    Glyxambi has been a miracle drug for me! I’ve taken it for 1 1/2 years, lost 35 pounds, have tons of energy & sleep great at night! I was just informed yesterday that my insurance will no longer cover the medicine so I will be paying for it out of pocket! One pill once a day & my blood sis completely under control!

  2. Joel Silverman says:

    I think that it is perverse that individuals still blame the evil pharmaceutical companies, or the mean and nasty physician, or rotten FDA for their issues with Diabetes. Try to understand that despite your unobjective feelings, the medical field is not out to kill you and harvest your body. Medications have risks and side effects. Diet and exercise is always the appropriate first step, however, these drugs have also saved lives. Try to leave the drama and paranoia out of your assessment of Diabetes and the health care field.

    • Martin Hum says:

      Thank you for your comment on Real Diabetes Truth.

      Drama and paranoia are, as you suggest, unhelpful when talking about health issues. And, of course, we agree that some drugs can save lives or make life bearable. But the medicinal model of healthcare sometimes goes beyond reason, with over-prescription now a recognised problem.

      And, if our feelings are “unobjective”, so, too, must be those of a pharmaceutical industry that is focused on selling its products! Doctors do their best for their patients, but most submit to an immersion course in conventional medication that leaves them little time to fully explore other, evidence-based approaches.

      Real Diabetes Truth aims to highlight the dangers diabetes drugs can pose and research that shows there may be safer, equally effective alternatives.

      • Arthur Bloom says:

        The problem with what Joel is saying is that it also sounds a bit “paranoid” and “unobjective”. Of course, the pharmacuetical industry is making money out of patients and of course the driving force behind Big Pharma’s “ecocnomy” is disease.

        While I’m sure not all doctors see their patients as cashcows, I’m also not so blind as to not see how many doctors see what they do as a business… If diet and exercise are the foundation of good health, why do doctors and nurses only get an hour training in nutrition in their enitire 7 years of studying. And that’s a fact! However, they are constantly sent on seminars about new pharmacuetical breakthroughs – so clearly their is no balance and therefor also no objectivity.

        If anything, this article is well-written and simply states the facts about the dangers of a drug, including a flawed approval process. Dangers many doctors are not likely to discuss with their patients.

    • George says:

      Have we read the same article Joel?

      I see no paranoia or unobjective feelings or whatever trite you read into what the editor is saying.

      I read an article that questions the culture of pushing dangerous drugs to patients. And yes, it’s a culture (business) that needs to be questioned, because there are plenty of drugs (and doctors!) that do more harm than good.

      You just need to read some of the comments from patients that have been affected by this industry on the other articles posted on this blog to see what is really going on.

      I’m afraid to say you might stand alone in your unobjective opinion…

  3. CM says:

    I was put on Glyxambi in May, after getting T2 at 337gl and 13 A1c, also two types of insulin and metformin. I have now lost 31 lbs, my fasting is at 99; Alc at 5.8 and stopped all insulin; but feeling dizzy, in a daze and tired. Stopped taking the Glyxambi on Saturday the 29th after reading this webblog. Felt way better that night, Sunday I felt terrific and today feel wonderful. I will not take that drug ever again, not worth the horrible feeling I lived with every day.

    • Ruth Scott says:

      Well, if you listen to what Dr. Silverman has to say then your personal account of your experience with this drug is “unobjective”, “paranoid” and “dramatic”… Very much the same as my own experience of taking Glyxambi. But here’s the problem: Doctors DON’T listen to what their patients have to say. Doctors DON’T care when the side effects are so horrendous that you’d rather die, because doctors DON’T make money if their patients stop taking the drugs they prescribe.

  4. Jon says:

    Glyxambi side effects are worse than T2D in my opinion. I was prescribed this drug from my doctor and ever since taking it I’ve felt worse and worse each day. Some days I’m almost non-functional and spend hours in a daze. I feel dizzy constantly, and have allergy like symptoms so I began taking Claritin. But pollen count is dismal and still have the same allergy feeling after waking up. I am not going to take any more experimental drugs for my T2D.

    When I moved to Ireland and had begun to walk about the city for a few months my A1c was 7. My glucose was measured at around 127 as an average. I felt so much better and eventually rode my bicycle to-and-from work everyday (about 8 miles round trip). My wife and I walked an average of 20 kilometers a week and sometimes up to 30 or more when we lived in the city centre.

    Since returning to America I’ve been sick again and my Ac1 is around 8, but not so bad that I should take medications that make me feel like crap every day.

    I’m off this medication for good. I’ll continue to take Metformin for now and increase my physical activities to help control my T2D like I did in Ireland for 3,5 years.

    Cheers,

    Jon

    • Mary Wilson says:

      For ANYONE out there taking Metformin, please be aware that it can cause a depletion in Vitamin B12, and thus cause neuropathy; in my case, it only my hands that are affected, but bad news for a music(piano) teacher. My GP couldn’t have been less interested, and neglected to refer me to my Diabetic Consultant, and the condition progressed to crippling pain, usually at night, so lack of sleep combined with reduced ability to play/teach meant severe depression. All could have been avoided if I had been warned about the Metformin, and eventually, I found Alpha-lipoic(Thioctic)acid which got rid of the pain in less than a week -the numbness and inability to use my hands/fingers remains, that part of it all is irreversible, as it has gone on too long to be properly sorted out. Take Vit.B12 routinely,and you will avoid a lot of grief!

  5. Karen says:

    in essence what I’m trying to say is that perhaps the guidelines for when we need to take maintenance drugs have been lowered so much so that most Americans over the age of 50 are on at least several types of medications. perhaps if normal weren’t defined as such a very low target perhaps as a target only a 20 year old could attain then so many Americans would not be on so many drugs. these drugs can interact with each other and have numerous side effects which can cause a cascade of other and real medical problems.

    besides extremely high blood sugar a1c of 16.5, with all of the medications I suffered hair loss, heart palpitations, muscle aches… I was unable to be able to sit still for more than 30 minutes without my body aching, nasal drip, a pain in my right side towards the back, a pain in my neck and and shoulder it was difficult to hold my head up at times, two different types of arthritis, etc etc. I have regained my health through natural means.

    now I AM of the believe that blood pressure should be around100 plus your age. I remember hearing this in the late seventies, perhaps early eighties. I will no longer attempt to get my blood pressure down to a hundred and twenty.

  6. Karen says:

    food & lifestyle are often the blame for the higher rates of diabetes in the industrial world. but how about the possibility that maybe over the last 50 years what constitutes diabetes meaning the threshold defining when a person is defined as being diabetic has possibly been lowered several times over by persons who have direct us to the pharmaceutical industry. I read in approximately the 7Os to be defined as diabetic a person had to have a fasting blood sugar level of 200 and above. I’ve read that over a number of years it’s been lowered until now it is and some places 100 or more that defines you as diabetic.

    also consider that the medical industry considers having quote on quote high blood pressure, another set of numbers which has been lowered and lowered several times over the last few decades, it’s a sign that you could develop diabetes. I’ve read in one newspaper that it’s been known since the fifties but many high blood pressure medications destroy the body’s ability to metabolise sugar. so if you are diagnosed by a doctor as having high blood pressure and then you take the medicine for it you may well be on your way to developing diabetes. this is what happened to me my fasting blood sugar was below 100 after approximately 6 months of taking high blood pressure medication my fasting blood sugar was well over 200. later I kept forgetting to take the high blood pressure medication and my blood sugar fell back to what I would consider a normal range. as you can tell I am distrustful of conventional medical standards for what oh where are your numbers should be.